Levi A

نویسندگان

  • Levi A. Gheber
  • Ilse Katz
چکیده

A novel approach to “direct-write” negative nano-lithography, based on biological specificity, where a proteolytic enzyme is used to etch grooves in a hardened protein layer. We are using trypsin to engrave features in a BSA layer, while flowing the trypsin solution via a nano-pipette (controlled by a SPM) to the surface. Trypsin is a proteolytic enzyme that cleaves very specifically on the carboxyl side of lysine and arginine residues.

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تاریخ انتشار 2013